What is K9 Advantix? K9 Advantix (imidacloprid + permethrin) is a convenient monthly preventative for dogs that both repels and kills fleas, ticks, and mosquitoes. K9-Advantix also kills lice and repels biting flies. Because it repels and kills, K9 Advantix offers a more comprehensive protection against fleas & ticks in comparison to other veterinarian-recommended brands. K9 Advantix stops biting fleas within three to five minutes and kills 98-100 percent within 12 hours. (4 Pack = 4 doses which lasts 4 months.) Use Advantage for cats - K9 Advantix is not for use on cats. For: Dogs (only over 7 weeks of age or older) Benefits: • Kills & repels fleas, ticks, & mosquitoes • Stops fleas from biting your pet in 3-5 minutes providing fast relief • Kills adult fleas within 12 hours • Kills flea larvae in under 20 minutes • Repels disease-carrying mosquitoes before they bite • Stops ticks from attaching and reduces risk of Lyme Disease & tickborne diseases • Still works after your pet swims or is bathed How it works: K9 Advantix combines imidacloprid and permethrin to repel and kill fleas, ticks, and mosquitoes. Each ingredient begins to affect pests on contact, attacking parasite nerve cells at different sites. When combined, the two compounds overwhelm the parasite's nervous system. This leads to rapid paralysis and death of the parasite. It repels and kills ticks before they can attach. K9 Advantix repels and kills mosquitoes before they can bite. Cautions: Do not use on cats. Cats cannot metabolize the ingredients used in this product. In households with cats, separate the treated dog for about one hour until the product is thoroughly dry.